| Experiment ID | 
                                                                                                        226 | 
                                                                                                        
                                                                                                            
                                                                                                                
                                                                                                                    | MISEV standards | 
                                                                                                                 
                                                                                                                
                                                                                                                    | 
                                                                                                                                                                                                                                                    ✔
                                                                                                                             
                                                                                                                                EM
                                                                                                                             
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     | 
                                                                                                                    Biophysical techniques | 
                                                                                                                 
                                                                                                                
                                                                                                                    | 
                                                                                                                                                                                                                                                    ✔
                                                                                                                             
                                                                                                                                GAPDH|CD9|FLOT1
                                                                                                                             
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     | 
                                                                                                                    Enriched markers | 
                                                                                                                 
                                                                                                               
                                                                                                                
                                                                                                                    | 
                                                                                                                                                                                                                                                    ✔
                                                                                                                             
                                                                                                                                LMNA|H2AFX|ATP5A1|TOMM20
                                                                                                                             
                                                                                                                            
                                                                                                                                                                                                                                                                                                                                                                     | 
                                                                                                                    Negative markers | 
                                                                                                                 
                                                                                                                
                                                                                                                    | 
                                                                                                                                                                                                                                                                                                                                                                            ✘
                                                                                                                                                                                                                                             | 
                                                                                                                    
                                                                                                                        Particle analysis
                                                                                                                     | 
                                                                                                                 
                                                                                                             
                                                                                                         | 
                                                                                                    
                                                                                                    
                                                                                                        | Identified molecule | 
                                                                                                        
                                                                                                            ncRNA
                                                                                                                                                                                                                                                                                                                                                                                                                                                         | 
                                                                                                    
                                                                                                    
                                                                                                        | Identification method | 
                                                                                                        
                                                                                                                                                                                                                            Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
                                                                                                                                                                                                                             | 
                                                                                                    
                                                                                                    
                                                                                                        | PubMed ID | 
                                                                                                        
                                                                                                                                                                                                                            26027894
                                                                                                                        
                                                                                                                                                                                                                             | 
                                                                                                    
                                                                                                    
                                                                                                        | Organism | 
                                                                                                        Homo sapiens | 
                                                                                                    
                                                                                                    
                                                                                                        | Experiment description | 
                                                                                                        "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" | 
                                                                                                    
                                                                                                    
                                                                                                        | Authors | 
                                                                                                        "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" | 
                                                                                                    
                                                                                                    
                                                                                                        | Journal name | 
                                                                                                        
                                                                                                                                                                                                                            Journal of Extracellular Vesicles
                                                                                                                                                                                                                         | 
                                                                                                    
                                                                                                    
                                                                                                        | Publication year | 
                                                                                                        2015 | 
                                                                                                    
                                                                                                    
                                                                                                        | Sample | 
                                                                                                        Endothelial cells | 
                                                                                                    
                                                                                                    
                                                                                                        | Sample name | 
                                                                                                        HMEC-1 | 
                                                                                                    
                                                                                                    
                                                                                                    
                                                                                                        | Isolation/purification methods | 
                                                                                                        Differential ultracentrifugation Sucrose density gradient | 
                                                                                                    
                                                                                                    
                                                                                                        | Flotation density | 
                                                                                                        
                                                                                                                                                                                                                                                                                                                                        1.10 g/mL
                                                                                                                                                                                                                        
                                                                                                         | 
                                                                                                    
                                                                                                    
                                                                                                        | Molecules identified in the study | 
                                                                                                        miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA | 
                                                                                                    
                                                                                                    
                                                                                                        | Methods used in the study | 
                                                                                                        Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting |