Gene description for IRAK1BP1
Gene name interleukin-1 receptor-associated kinase 1 binding protein 1
Gene symbol IRAK1BP1
Other names/aliases AIP70
SIMPL
Species Homo sapiens
 Database cross references - IRAK1BP1
ExoCarta ExoCarta_134728
Entrez Gene 134728
HGNC 17368
MIM 615375
UniProt Q5VVH5  
 IRAK1BP1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for IRAK1BP1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    transcription, DNA-templated GO:0006351 IEA
    I-kappaB kinase/NF-kappaB signaling GO:0007249 ISS
    immune response GO:0006955 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified IRAK1BP1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IRAK1BP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IRAK1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which IRAK1BP1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here