Gene description for HMGB1P1
Gene name
high mobility group box 1 pseudogene 1
Gene symbol
HMGB1P1
Other names/aliases
HMG1L1 HMG1L7 HMGB1L1 dJ579F20.1
Species
Homo sapiens
Database cross references - HMGB1P1
ExoCarta
ExoCarta_10357
Vesiclepedia
VP_10357
Entrez Gene
10357
HGNC
4993
HMGB1P1 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells
35333565
Retinal pigment epithelial cells
35333565
Gene ontology annotations for HMGB1P1
Experiment description of studies that identified HMGB1P1 in sEVs
1
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for HMGB1P1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PER2
Proximity Label-MS
Homo sapiens
2
PTMS
5763
Affinity Capture-MS
Homo sapiens
3
NEDD4
4734
Affinity Capture-MS
Homo sapiens
4
ANP32A
8125
Affinity Capture-MS
Homo sapiens
5
METTL14
Affinity Capture-MS
Homo sapiens
6
HMGB1
3146
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
7
EIF6
3692
Affinity Capture-MS
Homo sapiens
8
CALML5
51806
Affinity Capture-MS
Homo sapiens
9
PDIA4
9601
Affinity Capture-MS
Homo sapiens
10
REG3G
Affinity Capture-MS
Homo sapiens
11
CALM1
801
Affinity Capture-MS
Homo sapiens
12
TKT
7086
Affinity Capture-MS
Homo sapiens
13
PEBP1
5037
Affinity Capture-MS
Homo sapiens
14
PARK7
11315
Affinity Capture-MS
Homo sapiens
15
BASP1
10409
Affinity Capture-MS
Homo sapiens
16
TCL1B
Affinity Capture-MS
Homo sapiens
17
EZH2
Affinity Capture-MS
Homo sapiens
18
SDF2L1
23753
Affinity Capture-MS
Homo sapiens
19
SUMO2
6613
Affinity Capture-MS
Homo sapiens
20
STMN1
3925
Affinity Capture-MS
Homo sapiens
21
PGAM1
5223
Affinity Capture-MS
Homo sapiens
22
RSAD2
Affinity Capture-MS
Homo sapiens
23
HMGA1
3159
Affinity Capture-MS
Homo sapiens
24
ABCE1
6059
Affinity Capture-MS
Homo sapiens
25
MED28
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which HMGB1P1 is involved
No pathways found