Gene description for ERMN
Gene name ermin, ERM-like protein
Gene symbol ERMN
Other names/aliases JN
KIAA1189
ermin
Species Homo sapiens
 Database cross references - ERMN
ExoCarta ExoCarta_57471
Vesiclepedia VP_57471
Entrez Gene 57471
HGNC 29208
MIM 610072
UniProt Q8TAM6  
 ERMN identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ERMN
Molecular Function
    protein binding GO:0005515 IPI
    actin filament binding GO:0051015 IBA
Biological Process
    morphogenesis of a branching structure GO:0001763 IBA
    actin filament organization GO:0007015 IBA
    actin filament organization GO:0007015 IDA
    regulation of cell shape GO:0008360 IBA
    regulation of cell shape GO:0008360 IDA
    regulation of cell projection organization GO:0031344 IBA
    regulation of cell projection organization GO:0031344 IDA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytoskeleton GO:0005856 IEA
    cell cortex GO:0005938 IBA
    cell cortex GO:0005938 IDA
    filopodium GO:0030175 IBA
    internode region of axon GO:0033269 IBA
    internode region of axon GO:0033269 IDA
    paranode region of axon GO:0033270 IBA
    paranode region of axon GO:0033270 IDA
    neuronal cell body GO:0043025 IBA
    myelin sheath GO:0043209 IBA
    extracellular exosome GO:0070062 HDA
    glial cell projection GO:0097386 IEA
 Experiment description of studies that identified ERMN in sEVs
1
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ERMN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 NEDD4 4734
Biochemical Activity Homo sapiens
3 RTN4IP1  
Two-hybrid Homo sapiens
4 SULT4A1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 CUL7 9820
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ERMN is involved
No pathways found





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