Gene description for SLC2A6
Gene name solute carrier family 2 (facilitated glucose transporter), member 6
Gene symbol SLC2A6
Other names/aliases GLUT6
GLUT9
HSA011372
Species Homo sapiens
 Database cross references - SLC2A6
ExoCarta ExoCarta_11182
Entrez Gene 11182
HGNC 11011
MIM 606813
UniProt Q9UGQ3  
 SLC2A6 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for SLC2A6
Molecular Function
    sugar:proton symporter activity GO:0005351 IBA
    glucose transmembrane transporter activity GO:0005355 NAS
Biological Process
    proton transport GO:0015992 IBA
    hexose transmembrane transport GO:0035428 IBA
    transmembrane transport GO:0055085 TAS
    glucose import GO:0046323 IBA
Subcellular Localization
    membrane GO:0016020 NAS
    integral component of plasma membrane GO:0005887 IBA
    plasma membrane GO:0005886 TAS
 Experiment description of studies that identified SLC2A6 in exosomes
1
Experiment ID 237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for SLC2A6
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC2A6 is involved
PathwayEvidenceSource
Facilitative Na+-independent glucose transporters TAS Reactome





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