Gene description for Egln1
Gene name	egl-9 family hypoxia-inducible factor 1
Gene symbol	Egln1
Other names/aliases	AI503754 C1orf12 HIF-PH2 HPH-2 Hif-p4h-2 ORF13 Phd2 SM-20
Species	Mus musculus
Database cross references - Egln1
ExoCarta	ExoCarta_112405
Entrez Gene	112405
UniProt	Q91YE3
Egln1 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Egln1

Molecular Function     oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0016706 ISO     enzyme binding GO:0019899 ISO     dioxygenase activity GO:0051213 IEA     peptidyl-proline 4-dioxygenase activity GO:0031545 ISO     oxidoreductase activity GO:0016491 IEA     oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 IEA     L-ascorbic acid binding GO:0031418 IEA     metal ion binding GO:0046872 IEA     peptidyl-proline dioxygenase activity GO:0031543 ISO     iron ion binding GO:0005506 IEA Biological Process     negative regulation of cyclic-nucleotide phosphodiesterase activity GO:0051344 ISO     oxidation-reduction process GO:0055114 ISO     cardiac muscle tissue morphogenesis GO:0055008 IMP     response to hypoxia GO:0001666 ISO     negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 ISO     regulation of angiogenesis GO:0045765 IMP     ventricular septum morphogenesis GO:0060412 IMP     peptidyl-proline hydroxylation to 4-hydroxy-L-proline GO:0018401 ISO     oxygen homeostasis GO:0032364 ISO     heart trabecula formation GO:0060347 IMP     response to nitric oxide GO:0071731 ISO     labyrinthine layer development GO:0060711 IMP     negative regulation of cAMP catabolic process GO:0030821 ISO Subcellular Localization     cytoplasm GO:0005737 ISO     nucleus GO:0005634 IEA     cytosol GO:0005829 ISO