Gene description for Prss1
Gene name protease, serine 1 (trypsin 1)
Gene symbol Prss1
Other names/aliases Try-1
Species Mus musculus
 Database cross references - Prss1
ExoCarta ExoCarta_114228
Entrez Gene 114228
 Prss1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Prss1
Molecular Function
    serine-type endopeptidase activity GO:0004252 IBA
Biological Process
    proteolysis GO:0006508 IBA
    digestion GO:0007586 IBA
Subcellular Localization
    extracellular space GO:0005615 IBA
 Experiment description of studies that identified Prss1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Prss1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Prss1 is involved
No pathways found

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