Gene description for Acp1
Gene name acid phosphatase 1, soluble
Gene symbol Acp1
Other names/aliases 4632432E04Rik
AI427468
Acp-1
LMW-PTP
Species Mus musculus
 Database cross references - Acp1
ExoCarta ExoCarta_11431
Entrez Gene 11431
UniProt Q9D358  
 Acp1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Acp1
Molecular Function
    acid phosphatase activity GO:0003993 IDA
    protein tyrosine phosphatase activity GO:0004725 IEA
    hydrolase activity GO:0016787 IEA
    phosphoprotein phosphatase activity GO:0004721 IEA
    phosphatase activity GO:0016791 IDA
    non-membrane spanning protein tyrosine phosphatase activity GO:0004726 IEA
Biological Process
    protein dephosphorylation GO:0006470 IEA
    dephosphorylation GO:0016311 IDA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    cytoplasmic side of plasma membrane GO:0009898 ISO
 Experiment description of studies that identified Acp1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Acp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ctnnb1  
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Acp1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here