Gene description for Suclg1
Gene name succinate-CoA ligase, alpha subunit
Gene symbol Suclg1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Suclg1
ExoCarta ExoCarta_114597
Vesiclepedia VP_114597
Entrez Gene 114597
UniProt P13086  
 Suclg1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Suclg1
Molecular Function
    nucleotide binding GO:0000166 IEA
    succinate-CoA ligase (ADP-forming) activity GO:0004775 IBA
    succinate-CoA ligase (ADP-forming) activity GO:0004775 IDA
    succinate-CoA ligase (ADP-forming) activity GO:0004775 IEA
    succinate-CoA ligase (GDP-forming) activity GO:0004776 IBA
    succinate-CoA ligase (GDP-forming) activity GO:0004776 IDA
    succinate-CoA ligase (GDP-forming) activity GO:0004776 IEA
    GDP binding GO:0019003 IDA
    protein-containing complex binding GO:0044877 IDA
Biological Process
    tricarboxylic acid cycle GO:0006099 IBA
    tricarboxylic acid cycle GO:0006099 IDA
    tricarboxylic acid cycle GO:0006099 IEA
    succinyl-CoA metabolic process GO:0006104 IDA
    succinate metabolic process GO:0006105 IDA
Subcellular Localization
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IEA
    succinate-CoA ligase complex (ADP-forming) GO:0009361 IBA
    protein-containing complex GO:0032991 IDA
    succinate-CoA ligase complex (GDP-forming) GO:0045244 IDA
    succinate-CoA ligase complex (GDP-forming) GO:0045244 ISO
 Experiment description of studies that identified Suclg1 in exosomes
1
Experiment ID 225
MISEV standards
EM
Biophysical techniques
GAPDH|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Suclg1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Itm2b 290364
Affinity Capture-MS Rattus norvegicus
2 Park7 117287
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Suclg1 is involved
PathwayEvidenceSource
Aerobic respiration and respiratory electron transport IEA Reactome
Citric acid cycle (TCA cycle) IEA Reactome
Metabolism IEA Reactome





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