Gene description for Suclg1
Gene name succinate-CoA ligase, alpha subunit
Gene symbol Suclg1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Suclg1
ExoCarta ExoCarta_114597
Entrez Gene 114597
UniProt P13086  
 Suclg1 identified in exosomes derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Suclg1
Molecular Function
    protein heterodimerization activity GO:0046982 IDA
    GTP binding GO:0005525 IEA
    succinate-CoA ligase (GDP-forming) activity GO:0004776 IDA
    GDP binding GO:0019003 IDA
    poly(A) RNA binding GO:0044822 ISO
    ATP citrate synthase activity GO:0003878 IEA
    cofactor binding GO:0048037 IEA
    succinate-CoA ligase (ADP-forming) activity GO:0004775 IDA
Biological Process
    succinyl-CoA metabolic process GO:0006104 IDA
    succinate metabolic process GO:0006105 IDA
    tricarboxylic acid cycle GO:0006099 IEA
Subcellular Localization
    mitochondrial inner membrane GO:0005743 ISO
    cytoplasm GO:0005737 ISO
    plasma membrane GO:0005886 ISO
    mitochondrion GO:0005739 ISO
    protein complex GO:0043234 IDA
    extracellular exosome GO:0070062 ISO
    succinate-CoA ligase complex (GDP-forming) GO:0045244 IDA
 Experiment description of studies that identified Suclg1 in exosomes
1
Experiment ID 225
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors Lee JE, Moon PG, Lee IK, Baek MC
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Suclg1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Suclg1 is involved
PathwayEvidenceSource
Citric acid cycle (TCA cycle) IEA Reactome





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