Gene description for SLITRK1
Gene name SLIT and NTRK-like family, member 1
Gene symbol SLITRK1
Other names/aliases LRRC12
TTM
Species Homo sapiens
 Database cross references - SLITRK1
ExoCarta ExoCarta_114798
Entrez Gene 114798
HGNC 20297
MIM 609678
UniProt Q96PX8  
 SLITRK1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SLITRK1
Biological Process
    adult behavior GO:0030534 IEA
    homeostatic process GO:0042592 IEA
    multicellular organism growth GO:0035264 IEA
    axonogenesis GO:0007409 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified SLITRK1 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SLITRK1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLITRK1 is involved
No pathways found





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