Gene description for Eif4e
Gene name	eukaryotic translation initiation factor 4E
Gene symbol	Eif4e
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Eif4e
ExoCarta	ExoCarta_117045
Vesiclepedia	VP_117045
Entrez Gene	117045
UniProt	P63074
Eif4e identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Eif4e

Molecular Function     RNA 7-methylguanosine cap binding GO:0000340 IBA     RNA 7-methylguanosine cap binding GO:0000340 ISO     RNA 7-methylguanosine cap binding GO:0000340 ISS     RNA binding GO:0003723 IEA     translation initiation factor activity GO:0003743 IBA     translation initiation factor activity GO:0003743 IEA     translation initiation factor activity GO:0003743 ISO     translation initiation factor activity GO:0003743 ISS     translation initiation factor activity GO:0003743 TAS     protein binding GO:0005515 IPI     enzyme binding GO:0019899 ISO     enzyme binding GO:0019899 ISS     eukaryotic initiation factor 4G binding GO:0031370 IPI     eukaryotic initiation factor 4G binding GO:0031370 ISO     mRNA cap binding GO:0098808 IEA     mRNA cap binding GO:0098808 ISO     mRNA cap binding GO:0098808 ISS     DNA-binding transcription factor binding GO:0140297 ISO     DNA-binding transcription factor binding GO:0140297 ISS Biological Process     G1/S transition of mitotic cell cycle GO:0000082 ISO     behavioral fear response GO:0001662 IEA     behavioral fear response GO:0001662 ISO     mRNA export from nucleus GO:0006406 IEA     mRNA export from nucleus GO:0006406 ISO     mRNA export from nucleus GO:0006406 ISS     translation GO:0006412 ISO     translational initiation GO:0006413 IBA     translational initiation GO:0006413 IEA     translational initiation GO:0006413 ISO     translational initiation GO:0006413 ISS     regulation of translation GO:0006417 IEA     regulation of translation GO:0006417 ISO     regulation of translation GO:0006417 ISS     negative regulation of autophagy GO:0010507 ISO     negative regulation of translation GO:0017148 IEA     negative regulation of translation GO:0017148 ISO     stem cell population maintenance GO:0019827 IEA     stem cell population maintenance GO:0019827 ISO     neuron differentiation GO:0030182 IEA     neuron differentiation GO:0030182 ISO     lung development GO:0030324 IEP     negative regulation of neuron differentiation GO:0045665 IEA     negative regulation of neuron differentiation GO:0045665 ISO     positive regulation of mitotic cell cycle GO:0045931 ISO     mRNA transport GO:0051028 IEA     nuclear export GO:0051168 ISO     cellular response to dexamethasone stimulus GO:0071549 IEA     cellular response to dexamethasone stimulus GO:0071549 ISO     regulation of translation at postsynapse, modulating synaptic transmission GO:0099578 IEA     regulation of translation at postsynapse, modulating synaptic transmission GO:0099578 ISO Subcellular Localization     P-body GO:0000932 ISO     P-body GO:0000932 ISS     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     cytosol GO:0005829 ISO     cytosol GO:0005829 ISS     cytoplasmic stress granule GO:0010494 ISO     cytoplasmic stress granule GO:0010494 ISS     eukaryotic translation initiation factor 4F complex GO:0016281 IBA     eukaryotic translation initiation factor 4F complex GO:0016281 IDA     eukaryotic translation initiation factor 4F complex GO:0016281 ISO     RISC complex GO:0016442 ISO     nuclear body GO:0016604 IEA     nuclear body GO:0016604 ISO     nuclear body GO:0016604 ISS     nuclear speck GO:0016607 ISO     nuclear speck GO:0016607 ISS     protein-containing complex GO:0032991 IDA     chromatoid body GO:0033391 IEA     chromatoid body GO:0033391 ISO     cytoplasmic ribonucleoprotein granule GO:0036464 ISO     perinuclear region of cytoplasm GO:0048471 ISO     perinuclear region of cytoplasm GO:0048471 ISS     postsynapse GO:0098794 IDA     postsynapse GO:0098794 IEA     postsynapse GO:0098794 ISO     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO     postsynaptic cytosol GO:0099524 IDA