Gene description for Aprt
Gene name adenine phosphoribosyl transferase
Gene symbol Aprt
Other names/aliases C85684
Species Mus musculus
 Database cross references - Aprt
ExoCarta ExoCarta_11821
Entrez Gene 11821
UniProt P08030  
 Aprt identified in exosomes derived from the following tissue/cell type
Brain cancer cells 19109410    
 Gene ontology annotations for Aprt
Molecular Function
    transferase activity, transferring glycosyl groups GO:0016757 IEA
    adenine phosphoribosyltransferase activity GO:0003999 IMP
    AMP binding GO:0016208 ISO
    adenine binding GO:0002055 IDA
    transferase activity GO:0016740 IEA
Biological Process
    grooming behavior GO:0007625 IGI
    lactation GO:0007595 ISO
    purine ribonucleoside salvage GO:0006166 IMP
    adenine salvage GO:0006168 IMP
    nucleoside metabolic process GO:0009116 IEA
    adenine metabolic process GO:0046083 IMP
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Aprt in exosomes
1
Experiment ID 26
ISEV standards
✔
EM
EV Biophysical techniques
✔
Alix|GAPDH|HSP70
EV Cytosolic markers
✔
CD9
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19109410    
Organism Mus musculus
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD
Journal name FASEB
Publication year 2008
Sample Brain cancer cells
Sample name SMA560vIII
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
 Protein-protein interactions for Aprt
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Aprt is involved
PathwayEvidenceSource
Purine salvage IEA Reactome





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