Gene description for Arf1
Gene name ADP-ribosylation factor 1
Gene symbol Arf1
Other names/aliases -
Species Mus musculus
 Database cross references - Arf1
ExoCarta ExoCarta_11840
Entrez Gene 11840
UniProt P84078  
 Arf1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Arf1
Molecular Function
    nucleotide binding GO:0000166 IEA
    GDP binding GO:0019003 ISO
    GTP binding GO:0005525 TAS
    magnesium ion binding GO:0000287 ISO
    poly(A) RNA binding GO:0044822 ISO
    protein homodimerization activity GO:0042803 ISO
    phospholipase D activator activity GO:1990583 ISO
    protein binding GO:0005515 IPI
Biological Process
    regulation of receptor internalization GO:0002090 ISO
    transport GO:0006810 IEA
    small GTPase mediated signal transduction GO:0007264 IEA
    vesicle-mediated transport GO:0016192 IDA
    lysosomal membrane organization GO:0097212 ISO
    positive regulation of calcium ion-dependent exocytosis GO:0045956 ISO
    regulation of phospholipid metabolic process GO:1903725 ISO
    positive regulation of sodium ion transmembrane transport GO:1902307 ISO
    positive regulation of catalytic activity GO:0043085 ISO
    positive regulation of late endosome to lysosome transport GO:1902824 ISO
    long term synaptic depression GO:0060292 ISO
    Golgi to transport vesicle transport GO:0055108 ISO
    very-low-density lipoprotein particle assembly GO:0034379 ISO
    positive regulation of endocytosis GO:0045807 ISO
    regulation of Arp2/3 complex-mediated actin nucleation GO:0034315 ISO
    cellular copper ion homeostasis GO:0006878 ISO
    synaptic vesicle budding GO:0070142 ISO
    positive regulation of ER to Golgi vesicle-mediated transport GO:1902953 ISO
    positive regulation of protein secretion GO:0050714 ISO
    protein transport GO:0015031 TAS
    actin filament organization GO:0007015 ISO
    dendritic spine organization GO:0097061 ISO
    positive regulation of dendritic spine development GO:0060999 ISO
Subcellular Localization
    COPI-coated vesicle GO:0030137 ISO
    cell junction GO:0030054 IEA
    synapse GO:0045202 IEA
    endomembrane system GO:0012505 IDA
    neuron projection GO:0043005 IEA
    membrane GO:0016020 IEA
    sarcomere GO:0030017 IDA
    intracellular GO:0005622 IEA
    cytosol GO:0005829 ISO
    cell leading edge GO:0031252 ISO
    peroxisomal membrane GO:0005778 ISO
    cytoplasm GO:0005737 IEA
    focal adhesion GO:0005925 ISO
    postsynaptic membrane GO:0045211 IEA
    late endosome GO:0005770 ISO
    trans-Golgi network GO:0005802 ISO
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IEA
    extracellular exosome GO:0070062 ISO
    Golgi membrane GO:0000139 ISO
 Experiment description of studies that identified Arf1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
2
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Arf1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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