Gene description for Rhoc
Gene name ras homolog gene family, member C
Gene symbol Rhoc
Other names/aliases AI324259
Arh9
Arhc
Species Mus musculus
 Database cross references - Rhoc
ExoCarta ExoCarta_11853
Entrez Gene 11853
UniProt Q62159  
 Rhoc identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Rhoc
Molecular Function
    signal transducer activity GO:0004871 ISO
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
    GTP binding GO:0005525 IEA
Biological Process
    cytokinesis GO:0000910 ISO
    positive regulation of lipase activity GO:0060193 ISO
    apical junction assembly GO:0043297 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
    signal transduction GO:0007165 ISO
    positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISO
Subcellular Localization
    plasma membrane GO:0005886 IDA
    extracellular exosome GO:0070062 ISO
    cleavage furrow GO:0032154 ISO
    membrane GO:0016020 ISO
    cytosol GO:0005829 ISO
    nucleus GO:0005634 IDA
    intracellular GO:0005622 IEA
 Experiment description of studies that identified Rhoc in exosomes
1
Experiment ID 73
ISEV standards
EM
EV Biophysical techniques
HSP70|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Rhoc
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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