Gene description for Arhgdib
Gene name Rho, GDP dissociation inhibitor (GDI) beta
Gene symbol Arhgdib
Other names/aliases D4
Gdid4
Ly-GDI
Species Mus musculus
 Database cross references - Arhgdib
ExoCarta ExoCarta_11857
Entrez Gene 11857
UniProt Q61599  
 Arhgdib identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Arhgdib
Molecular Function
    GTPase activity GO:0003924 ISO
    Rho GDP-dissociation inhibitor activity GO:0005094 IEA
    GTPase activator activity GO:0005096 IEA
Biological Process
    negative regulation of trophoblast cell migration GO:1901164 ISO
    metabolic process GO:0008152 ISO
Subcellular Localization
    membrane GO:0016020 ISO
    cytoplasm GO:0005737 IEA
    cytosol GO:0005829 ISO
    extracellular exosome GO:0070062 ISO
 Experiment description of studies that identified Arhgdib in exosomes
1
Experiment ID 73
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSP70|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Arhgdib
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Arhgdib is involved
PathwayEvidenceSource
Rho GTPase cycle IEA Reactome





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