Gene description for NLRP8
Gene name NLR family, pyrin domain containing 8
Gene symbol NLRP8
Other names/aliases CLR19.2
NALP8
NOD16
PAN4
Species Homo sapiens
 Database cross references - NLRP8
ExoCarta ExoCarta_126205
Vesiclepedia VP_126205
Entrez Gene 126205
HGNC 22940
MIM 609659
UniProt Q86W28  
 NLRP8 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for NLRP8
Molecular Function
    ATP binding GO:0005524 IEA
Biological Process
    regulation of inflammatory response GO:0050727 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified NLRP8 in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for NLRP8
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DNAJB4 11080
Affinity Capture-MS Homo sapiens
2 DNAJB5  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NLRP8 is involved
No pathways found





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