Gene description for Col18a1
Gene name collagen, type XVIII, alpha 1
Gene symbol Col18a1
Other names/aliases -
Species Mus musculus
 Database cross references - Col18a1
ExoCarta ExoCarta_12822
Entrez Gene 12822
UniProt P39061  
 Col18a1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Col18a1
Molecular Function
    identical protein binding GO:0042802 ISO
    structural molecule activity GO:0005198 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    positive regulation of cell proliferation GO:0008284 IDA
    positive regulation of endothelial cell apoptotic process GO:2000353 IDA
    endothelial cell morphogenesis GO:0001886 IDA
    angiogenesis GO:0001525 IMP
    positive regulation of cell migration GO:0030335 IDA
    extracellular matrix organization GO:0030198 IMP
    cell adhesion GO:0007155 IEA
Subcellular Localization
    extracellular space GO:0005615 ISO
    collagen trimer GO:0005581 IEA
    extracellular exosome GO:0070062 ISO
    proteinaceous extracellular matrix GO:0005578 IEA
    basement membrane GO:0005604 IDA
    extracellular matrix GO:0031012 ISO
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified Col18a1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Col18a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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