Gene description for Fbln2
Gene name fibulin 2
Gene symbol Fbln2
Other names/aliases 5730577E14Rik
Species Mus musculus
 Database cross references - Fbln2
ExoCarta ExoCarta_14115
Entrez Gene 14115
UniProt P37889  
 Fbln2 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Fbln2
Molecular Function
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
    extracellular matrix binding GO:0050840 IDA
Biological Process
    positive regulation of cell-substrate adhesion GO:0010811 IDA
Subcellular Localization
    proteinaceous extracellular matrix GO:0005578 IEA
    extracellular matrix GO:0031012 ISO
    extracellular exosome GO:0070062 ISO
    extracellular region GO:0005576 IEA
    extracellular vesicle GO:1903561 ISO
 Experiment description of studies that identified Fbln2 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Fbln2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fbln2 is involved
Molecules associated with elastic fibres IEA Reactome

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