Gene description for Col6a2
Gene name collagen, type VI, alpha 2
Gene symbol Col6a2
Other names/aliases Col6a-2
Species Mus musculus
 Database cross references - Col6a2
ExoCarta ExoCarta_12834
Entrez Gene 12834
UniProt Q02788  
 Col6a2 identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
Mast cells 17486113    
 Gene ontology annotations for Col6a2
Biological Process
    cell adhesion GO:0007155 IEA
    protein heterotrimerization GO:0070208 ISO
Subcellular Localization
    membrane GO:0016020 IEA
    extracellular matrix GO:0031012 ISO
    extracellular exosome GO:0070062 ISO
    extracellular region GO:0005576 ISO
    proteinaceous extracellular matrix GO:0005578 IDA
    collagen trimer GO:0005581 IEA
    sarcolemma GO:0042383 IDA
    extracellular vesicle GO:1903561 ISO
    extracellular space GO:0005615 ISO
    protein complex GO:0043234 ISO
 Experiment description of studies that identified Col6a2 in exosomes
1
Experiment ID 73
ISEV standards
EM
EV Biophysical techniques
HSP70|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
2
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Col6a2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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