Gene description for COL13A1
Gene name collagen, type XIII, alpha 1
Gene symbol COL13A1
Other names/aliases COLXIIIA1
Species Homo sapiens
 Database cross references - COL13A1
ExoCarta ExoCarta_1305
Vesiclepedia VP_1305
Entrez Gene 1305
HGNC 2190
MIM 120350
UniProt Q5TAT6  
 COL13A1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for COL13A1
Molecular Function
    heparin binding GO:0008201 IDA
    protein binding GO:0005515 IPI
Biological Process
    extracellular matrix disassembly GO:0022617 TAS
    morphogenesis of a branching structure GO:0001763 ISS
    single organismal cell-cell adhesion GO:0016337 IEP
    extracellular matrix organization GO:0030198 TAS
    cell-matrix adhesion GO:0007160 IPI
    cell differentiation GO:0030154 IEA
    collagen catabolic process GO:0030574 TAS
    endochondral ossification GO:0001958 ISS
Subcellular Localization
    endoplasmic reticulum lumen GO:0005788 TAS
    extracellular region GO:0005576 TAS
    plasma membrane GO:0005886 TAS
    collagen type XIII trimer GO:0005600 TAS
    cell-cell junction GO:0005911 IEA
 Experiment description of studies that identified COL13A1 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for COL13A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NID2 22795
Invitro Homo sapiens
2 NID1 4811
Invitro Homo sapiens
3 ITGA1 3672
Invivo Homo sapiens
4 FN1 2335
Invitro Homo sapiens
5 HSPG2 3339
Invitro Homo sapiens
6 SPARC 6678
Invitro Homo sapiens
7 COL13A1 1305
Invivo Homo sapiens
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which COL13A1 is involved
PathwayEvidenceSource
Collagen biosynthesis and modifying enzymes TAS Reactome
Collagen degradation TAS Reactome
Integrin cell surface interactions TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here