Gene description for Sparcl1
Gene name SPARC-like 1
Gene symbol Sparcl1
Other names/aliases Ecm2
Species Mus musculus
 Database cross references - Sparcl1
ExoCarta ExoCarta_13602
Entrez Gene 13602
UniProt P70663  
 Sparcl1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Sparcl1
Molecular Function
    metal ion binding GO:0046872 IEA
    calcium ion binding GO:0005509 IEA
Biological Process
    signal transduction GO:0007165 IEA
Subcellular Localization
    proteinaceous extracellular matrix GO:0005578 IEA
    synapse GO:0045202 ISO
    extracellular exosome GO:0070062 ISO
    extracellular region GO:0005576 IEA
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Sparcl1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sparcl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sparcl1 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here