Gene description for C9orf116
Gene name chromosome 9 open reading frame 116
Gene symbol C9orf116
Other names/aliases PIERCE1
RbEST47
Species Homo sapiens
 Database cross references - C9orf116
ExoCarta ExoCarta_138162
Entrez Gene 138162
HGNC 28435
MIM 614502
UniProt Q5BN46  
 C9orf116 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for C9orf116
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified C9orf116 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for C9orf116
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C9orf116 is involved
No pathways found





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