Gene description for Stom
Gene name stomatin
Gene symbol Stom
Other names/aliases Epb7.2
Species Mus musculus
 Database cross references - Stom
ExoCarta ExoCarta_13830
Entrez Gene 13830
UniProt P54116  
 Stom identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Stom
Molecular Function
    protein binding GO:0005515 IPI
    protein homodimerization activity GO:0042803 IPI
    identical protein binding GO:0042802 IPI
    RNA polymerase binding GO:0070063 ISO
Biological Process
    regulation of ion transmembrane transport GO:0034765 IDA
    protein homooligomerization GO:0051260 ISO
    regulation of acid-sensing ion channel activity GO:1901585 IDA
    positive regulation of protein targeting to membrane GO:0090314 IMP
    positive regulation of viral process GO:0048524 IMP
    positive regulation by host of viral genome replication GO:0044829 IMP
    positive regulation of defense response to virus by host GO:0002230 ISO
    activation of mitophagy in response to mitochondrial depolarization GO:0098779 ISO
Subcellular Localization
    vesicle GO:0031982 ISO
    mitochondrion GO:0005739 ISO
    membrane GO:0016020 ISO
    extracellular space GO:0005615 ISO
    cytoskeleton GO:0005856 ISO
    membrane raft GO:0045121 ISO
    cytoplasmic vesicle GO:0031410 IEA
    extracellular exosome GO:0070062 ISO
    blood microparticle GO:0072562 ISO
    plasma membrane GO:0005886 IEA
    perinuclear region of cytoplasm GO:0048471 IDA
    integral component of plasma membrane GO:0005887 ISO
    endoplasmic reticulum GO:0005783 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Stom in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Stom
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Stom is involved
No pathways found

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