Gene description for Erbb4
Gene name	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
Gene symbol	Erbb4
Other names/aliases	Her4 c-erbB-4
Species	Mus musculus
Database cross references - Erbb4
ExoCarta	ExoCarta_13869
Entrez Gene	13869
UniProt	Q61527
Erbb4 identified in exosomes derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Erbb4

Molecular Function     nucleotide binding GO:0000166 IEA     transcription regulatory region DNA binding GO:0044212 ISO     receptor signaling protein tyrosine kinase activity GO:0004716 IEA     transmembrane receptor protein tyrosine kinase activity GO:0004714 ISO     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     transferase activity, transferring phosphorus-containing groups GO:0016772 IEA     kinase activity GO:0016301 IEA     epidermal growth factor receptor binding GO:0005154 ISO     protein homodimerization activity GO:0042803 ISO     protein tyrosine kinase activity GO:0004713 ISO     protein kinase activity GO:0004672 IEA     transferase activity GO:0016740 IEA Biological Process     apoptotic process GO:0006915 IEA     peptidyl-tyrosine phosphorylation GO:0018108 ISO     embryonic pattern specification GO:0009880 IMP     protein autophosphorylation GO:0046777 ISO     positive regulation of cell migration GO:0030335 ISO     mammary gland alveolus development GO:0060749 IMP     mitochondrial fragmentation involved in apoptotic process GO:0043653 ISO     positive regulation of transcription, DNA-templated GO:0045893 ISO     positive regulation of ERK1 and ERK2 cascade GO:0070374 ISO     cell migration GO:0016477 ISO     positive regulation of epithelial cell proliferation GO:0050679 ISO     negative regulation of cell proliferation GO:0008285 ISO     positive regulation of cardiac muscle cell proliferation GO:0060045 IMP     synapse maturation GO:0060074 ISO     positive regulation of synaptic transmission, GABAergic GO:0032230 ISO     positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 ISO     protein phosphorylation GO:0006468 IEA     multicellular organismal development GO:0007275 IEA     regulation of transcription, DNA-templated GO:0006355 IEA     transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 ISO     positive regulation of cell proliferation GO:0008284 ISO     heart development GO:0007507 IMP     cardiac muscle tissue regeneration GO:0061026 IMP     positive regulation of STAT protein import into nucleus GO:2000366 ISO     positive regulation of glucose import GO:0046326 ISO     central nervous system morphogenesis GO:0021551 IMP     signal transduction GO:0007165 ISO     transcription, DNA-templated GO:0006351 IEA     negative regulation of muscle cell apoptotic process GO:0010656 ISO     cell fate commitment GO:0045165 IDA     negative regulation of apoptotic process GO:0043066 ISO     nervous system development GO:0007399 IMP     regulation of cell migration GO:0030334 IMP     mammary gland epithelial cell differentiation GO:0060644 IMP     surfactant homeostasis GO:0043129 ISO     lactation GO:0007595 ISO     phosphorylation GO:0016310 IEA     neural crest cell migration GO:0001755 IMP     olfactory bulb interneuron differentiation GO:0021889 IMP Subcellular Localization     nucleus GO:0005634 ISO     integral component of membrane GO:0016021 IEA     caveola GO:0005901 ISO     membrane raft GO:0045121 ISO     basolateral plasma membrane GO:0016323 ISO     mitochondrion GO:0005739 ISO     plasma membrane GO:0005886 ISO     postsynaptic density GO:0014069 ISO     membrane GO:0016020 IEA     receptor complex GO:0043235 ISO     cytoplasm GO:0005737 ISO