Gene description for Esd
Gene name esterase D/formylglutathione hydrolase
Gene symbol Esd
Other names/aliases Es-10
Es10
FGH
sid478
Species Mus musculus
 Database cross references - Esd
ExoCarta ExoCarta_13885
Entrez Gene 13885
UniProt Q9R0P3  
 Esd identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Esd
Molecular Function
    hydrolase activity, acting on ester bonds GO:0016788 ISO
    S-formylglutathione hydrolase activity GO:0018738 IEA
    hydrolase activity GO:0016787 IEA
    carboxylic ester hydrolase activity GO:0052689 IEA
Biological Process
    formaldehyde catabolic process GO:0046294 IEA
Subcellular Localization
    Golgi apparatus GO:0005794 ISO
    nucleoplasm GO:0005654 ISO
    cytoplasmic vesicle GO:0031410 IEA
    cytoplasm GO:0005737 ISO
    extracellular exosome GO:0070062 ISO
    plasma membrane GO:0005886 ISO
 Experiment description of studies that identified Esd in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Esd
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Esd is involved
No pathways found





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