Gene description for Gstm2
Gene name glutathione S-transferase, mu 2
Gene symbol Gstm2
Other names/aliases Gstb-2
Gstb2
Species Mus musculus
 Database cross references - Gstm2
ExoCarta ExoCarta_14863
Entrez Gene 14863
UniProt P15626  
 Gstm2 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Gstm2
Molecular Function
    glutathione transferase activity GO:0004364 ISO
    glutathione binding GO:0043295 ISO
    protein heterodimerization activity GO:0046982 IDA
    protein homodimerization activity GO:0042803 ISO
    enzyme binding GO:0019899 ISO
    transferase activity GO:0016740 IEA
Biological Process
    xenobiotic catabolic process GO:0042178 ISO
    glutathione metabolic process GO:0006749 ISO
    metabolic process GO:0008152 IEA
    cellular detoxification of nitrogen compound GO:0070458 ISO
    nitrobenzene metabolic process GO:0018916 ISO
Subcellular Localization
    cytosol GO:0005829 ISO
    protein complex GO:0043234 ISO
    plasma membrane GO:0005886 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Gstm2 in exosomes
1
Experiment ID 210
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD81|FLOT1
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gstm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gstm2 is involved
PathwayEvidenceSource
Glutathione conjugation IEA Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here