Gene description for Gstm2
Gene name glutathione S-transferase, mu 2
Gene symbol Gstm2
Other names/aliases Gstb-2
Gstb2
Species Mus musculus
 Database cross references - Gstm2
ExoCarta ExoCarta_14863
Vesiclepedia VP_14863
Entrez Gene 14863
UniProt P15626  
 Gstm2 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Gstm2
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 IDA
    glutathione transferase activity GO:0004364 ISO
    protein binding GO:0005515 IPI
    enzyme binding GO:0019899 ISO
    identical protein binding GO:0042802 IPI
    identical protein binding GO:0042802 ISO
    protein homodimerization activity GO:0042803 ISO
    glutathione binding GO:0043295 ISO
Biological Process
    glutathione metabolic process GO:0006749 IBA
    glutathione metabolic process GO:0006749 ISO
    xenobiotic catabolic process GO:0042178 ISO
    hepoxilin biosynthetic process GO:0051122 ISS
Subcellular Localization
    cytoplasm GO:0005737 ISO
    mitochondrion GO:0005739 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 ISO
    protein-containing complex GO:0032991 ISO
    intercellular bridge GO:0045171 ISO
 Experiment description of studies that identified Gstm2 in sEVs
1
Experiment ID 210
MISEV standards
EM
Biophysical techniques
CD81|FLOT1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Gstm2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSD17B10 3028
Affinity Capture-MS Homo sapiens
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