Gene description for Gsto1
Gene name glutathione S-transferase omega 1
Gene symbol Gsto1
Other names/aliases AA407097
AI194287
AU018802
GSTO 1-1
GSTX
SPG-R
p28
Species Mus musculus
 Database cross references - Gsto1
ExoCarta ExoCarta_14873
Vesiclepedia VP_14873
Entrez Gene 14873
UniProt O09131  
 Gsto1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Gsto1
Molecular Function
    glutathione transferase activity GO:0004364 IBA
    glutathione transferase activity GO:0004364 ISO
    glutathione transferase activity GO:0004364 ISS
    oxidoreductase activity GO:0016491 ISO
    oxidoreductase activity GO:0016491 ISS
    glutathione dehydrogenase (ascorbate) activity GO:0045174 IBA
    glutathione dehydrogenase (ascorbate) activity GO:0045174 ISO
    glutathione dehydrogenase (ascorbate) activity GO:0045174 ISS
    methylarsonate reductase activity GO:0050610 IEA
Biological Process
    glutathione metabolic process GO:0006749 IBA
    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 IEA
    regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 ISO
    L-ascorbic acid metabolic process GO:0019852 IBA
    L-ascorbic acid metabolic process GO:0019852 ISO
    L-ascorbic acid metabolic process GO:0019852 ISS
    L-ascorbic acid biosynthetic process GO:0019853 ISO
    xenobiotic catabolic process GO:0042178 ISO
    xenobiotic catabolic process GO:0042178 ISS
    negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 ISO
    positive regulation of ryanodine-sensitive calcium-release channel activity GO:0060316 ISO
    cellular response to arsenic-containing substance GO:0071243 ISO
    cellular response to arsenic-containing substance GO:0071243 ISS
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    basement membrane GO:0005604 ISO
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    cytosol GO:0005829 IEA
    axon GO:0030424 ISO
    nuclear membrane GO:0031965 ISO
    cell body GO:0044297 ISO
 Experiment description of studies that identified Gsto1 in sEVs
1
Experiment ID 907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Gsto1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSD17B10 3028
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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