Gene description for H2afx
Gene name	H2A histone family, member X
Gene symbol	H2afx
Other names/aliases	AW228881 H2A.X H2ax Hist5-2ax gammaH2ax
Species	Mus musculus
Database cross references - H2afx
ExoCarta	ExoCarta_15270
Entrez Gene	15270
UniProt	P27661
H2afx identified in exosomes derived from the following tissue/cell type
Fibroblasts	23260141
Mast cells	17486113

Gene ontology annotations for H2afx

Molecular Function     protein heterodimerization activity GO:0046982 IEA     protein binding GO:0005515 IPI     histone binding GO:0042393 ISO     DNA binding GO:0003677 IEA     enzyme binding GO:0019899 ISO     damaged DNA binding GO:0003684 IDA Biological Process     cellular response to DNA damage stimulus GO:0006974 ISO     DNA damage checkpoint GO:0000077 IMP     meiotic cell cycle GO:0051321 IEA     DNA recombination GO:0006310 IEA     DNA repair GO:0006281 IMP     spermatogenesis GO:0007283 IMP     cellular response to gamma radiation GO:0071480 ISO     double-strand break repair via homologous recombination GO:0000724 IMP     cell cycle GO:0007049 IEA Subcellular Localization     nucleosome GO:0000786 IEA     nucleus GO:0005634 ISO     nuclear chromatin GO:0000790 IDA     replication fork GO:0005657 IDA     male germ cell nucleus GO:0001673 IDA     condensed nuclear chromosome GO:0000794 IDA     chromosome, telomeric region GO:0000781 ISO     chromosome GO:0005694 IDA     XY body GO:0001741 IDA     extracellular exosome GO:0070062 ISO     chromatin GO:0000785 IDA     site of double-strand break GO:0035861 ISO