Gene description for Cd47
Gene name CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
Gene symbol Cd47
Other names/aliases 9130415E20Rik
AA407862
AI848868
AW108519
B430305P08Rik
IAP
Itgp
Species Mus musculus
 Database cross references - Cd47
ExoCarta ExoCarta_16423
Vesiclepedia VP_16423
Entrez Gene 16423
UniProt Q61735  
 Cd47 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Cd47
Molecular Function
    thrombospondin receptor activity GO:0070053 ISO
    protein binding GO:0005515 IPI
Biological Process
    opsonization GO:0008228 IDA
    positive regulation of inflammatory response GO:0050729 IMP
    signal transduction GO:0007165 ISO
    cell migration GO:0016477 ISO
    positive regulation of cell proliferation GO:0008284 ISO
    positive regulation of phagocytosis GO:0050766 IDA
    cell adhesion GO:0007155 IEA
    positive regulation of cell-cell adhesion GO:0022409 ISO
    response to bacterium GO:0009617 IMP
    positive regulation of T cell activation GO:0050870 ISO
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    plasma membrane GO:0005886 IEA
    extracellular exosome GO:0070062 ISO
    integral component of plasma membrane GO:0005887 IDA
    membrane GO:0016020 IEA
 Experiment description of studies that identified Cd47 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Cd47
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Ubqln2  
Reconstituted Complex Mus musculus
View the network image/svg+xml



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