Gene description for Krt14
Gene name keratin 14
Gene symbol Krt14
Other names/aliases AI626930
Species Mus musculus
 Database cross references - Krt14
ExoCarta ExoCarta_16664
Entrez Gene 16664
UniProt Q61781  
 Krt14 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt14
Molecular Function
    protein binding GO:0005515 IPI
    keratin filament binding GO:1990254 ISO
    structural molecule activity GO:0005198 IEA
Biological Process
    epithelial cell differentiation GO:0030855 ISO
    intermediate filament bundle assembly GO:0045110 ISO
    aging GO:0007568 ISO
    hair cycle GO:0042633 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    keratin filament GO:0045095 ISO
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
    intracellular GO:0005622 IDA
    intermediate filament GO:0005882 ISO
    cell periphery GO:0071944 IDA
 Experiment description of studies that identified Krt14 in exosomes
Experiment ID 33
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt14
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt14 is involved
Type I hemidesmosome assembly IEA Reactome

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