Gene description for Krt16
Gene name keratin 16
Gene symbol Krt16
Other names/aliases AI324768
Species Mus musculus
 Database cross references - Krt16
ExoCarta ExoCarta_16666
Entrez Gene 16666
UniProt Q9Z2K1  
 Krt16 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt16
Molecular Function
    structural constituent of cytoskeleton GO:0005200 IDA
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
Biological Process
    inflammatory response GO:0006954 IMP
    aging GO:0007568 ISO
    morphogenesis of an epithelium GO:0002009 IMP
    establishment of skin barrier GO:0061436 IMP
    immune system process GO:0002376 IEA
    hair cycle GO:0042633 ISO
    keratinocyte differentiation GO:0030216 IDA
    keratinization GO:0031424 IDA
    innate immune response GO:0045087 IMP
    keratinocyte migration GO:0051546 IDA
    negative regulation of cell migration GO:0030336 ISO
    intermediate filament cytoskeleton organization GO:0045104 IDA
Subcellular Localization
    cytoskeleton GO:0005856 ISO
    intermediate filament GO:0005882 IDA
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Krt16 in exosomes
Experiment ID 33
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt16
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt16 is involved
No pathways found

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