Gene description for Krt17
Gene name keratin 17
Gene symbol Krt17
Other names/aliases K17
Species Mus musculus
 Database cross references - Krt17
ExoCarta ExoCarta_16667
Entrez Gene 16667
UniProt Q9QWL7  
 Krt17 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt17
Molecular Function
    MHC class II receptor activity GO:0032395 ISO
    MHC class II protein binding GO:0042289 ISO
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of translation GO:0045727 IMP
    keratinization GO:0031424 IGI
    intermediate filament organization GO:0045109 IGI
    hair follicle morphogenesis GO:0031069 IMP
    positive regulation of hair follicle development GO:0051798 IMP
    positive regulation of cell growth GO:0030307 IMP
    morphogenesis of an epithelium GO:0002009 IGI
    signal transduction GO:0007165 ISO
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IDA
    intermediate filament GO:0005882 IEA
    cell periphery GO:0071944 IDA
 Experiment description of studies that identified Krt17 in exosomes
Experiment ID 33
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt17
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt17 is involved
No pathways found

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