Gene description for Krt1
Gene name keratin 1
Gene symbol Krt1
Other names/aliases Krt-2.1
Species Mus musculus
 Database cross references - Krt1
ExoCarta ExoCarta_16678
Entrez Gene 16678
UniProt P04104  
 Krt1 identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Krt1
Molecular Function
    structural molecule activity GO:0005198 IEA
    carbohydrate binding GO:0030246 ISO
Biological Process
    complement activation, lectin pathway GO:0001867 ISO
    negative regulation of inflammatory response GO:0050728 IMP
    establishment of skin barrier GO:0061436 IMP
Subcellular Localization
    extracellular matrix GO:0031012 ISO
    intermediate filament GO:0005882 IEA
    extracellular exosome GO:0070062 ISO
    keratin filament GO:0045095 IDA
    extracellular space GO:0005615 ISO
    blood microparticle GO:0072562 ISO
    membrane GO:0016020 ISO
    nucleus GO:0005634 ISO
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Krt1 in exosomes
Experiment ID 33
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Krt1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Krt1 is involved
No pathways found

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