Gene description for Slc40a1
Gene name	solute carrier family 40 (iron-regulated transporter), member 1
Gene symbol	Slc40a1
Other names/aliases	Fpn1 Slc11a3 Slc39a1
Species	Rattus norvegicus
Database cross references - Slc40a1
ExoCarta	ExoCarta_170840
Vesiclepedia	VP_170840
Entrez Gene	170840
UniProt	Q923U9
Slc40a1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Slc40a1

Molecular Function     iron ion transmembrane transporter activity GO:0005381 IBA     iron ion transmembrane transporter activity GO:0005381 IEA     iron ion transmembrane transporter activity GO:0005381 ISO     iron ion transmembrane transporter activity GO:0005381 NAS     ferrous iron transmembrane transporter activity GO:0015093 IEA     ferrous iron transmembrane transporter activity GO:0015093 ISO     peptide hormone binding GO:0017046 IBA     peptide hormone binding GO:0017046 IEA     peptide hormone binding GO:0017046 ISO     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     metal ion binding GO:0046872 IEA Biological Process     lymphocyte homeostasis GO:0002260 IEA     lymphocyte homeostasis GO:0002260 ISO     endothelium development GO:0003158 IEA     endothelium development GO:0003158 ISO     transcription by RNA polymerase II GO:0006366 IEA     transcription by RNA polymerase II GO:0006366 ISO     iron ion transport GO:0006826 ISO     iron ion transport GO:0006826 NAS     intracellular iron ion homeostasis GO:0006879 IEA     intracellular iron ion homeostasis GO:0006879 ISO     apoptotic process GO:0006915 IEA     apoptotic process GO:0006915 ISO     iron ion transmembrane transport GO:0034755 IBA     iron ion transmembrane transport GO:0034755 IEA     iron ion transmembrane transport GO:0034755 ISO     iron ion transmembrane transport GO:0034755 ISO     negative regulation of apoptotic process GO:0043066 IEA     negative regulation of apoptotic process GO:0043066 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     spleen development GO:0048536 ISO     establishment of localization in cell GO:0051649 IEA     establishment of localization in cell GO:0051649 ISO     spleen trabecula formation GO:0060345 IEA     spleen trabecula formation GO:0060345 ISO     multicellular organismal-level iron ion homeostasis GO:0060586 IEA     multicellular organismal-level iron ion homeostasis GO:0060586 ISO     multicellular organismal-level iron ion homeostasis GO:0060586 ISO     iron ion export across plasma membrane GO:1903988 IEA     iron ion export across plasma membrane GO:1903988 ISO     iron ion export across plasma membrane GO:1903988 ISS Subcellular Localization     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 ISO     synaptic vesicle GO:0008021 IEA     synaptic vesicle GO:0008021 ISO     basolateral plasma membrane GO:0016323 IBA     basolateral plasma membrane GO:0016323 IEA     basolateral plasma membrane GO:0016323 ISO     basolateral plasma membrane GO:0016323 ISO