Gene description for Mcm4
Gene name minichromosome maintenance deficient 4 homolog (S. cerevisiae)
Gene symbol Mcm4
Other names/aliases 19G
AI325074
AU045576
Cdc21
Mcmd4
mKIAA4003
mcdc21
Species Mus musculus
 Database cross references - Mcm4
ExoCarta ExoCarta_17217
Entrez Gene 17217
UniProt P49717  
 Mcm4 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Mcm4
Molecular Function
    ATP-dependent DNA helicase activity GO:0004003 ISO
    protein binding GO:0005515 IPI
    hydrolase activity GO:0016787 IEA
    DNA binding GO:0003677 IEA
    DNA helicase activity GO:0003678 IDA
    single-stranded DNA binding GO:0003697 IPI
    nucleotide binding GO:0000166 IEA
    helicase activity GO:0004386 IEA
    ATP binding GO:0005524 IEA
Biological Process
    DNA replication initiation GO:0006270 IEA
    DNA replication GO:0006260 IEA
    cell cycle GO:0007049 IEA
    DNA unwinding involved in DNA replication GO:0006268 IPI
Subcellular Localization
    nucleus GO:0005634 IEA
    nucleoplasm GO:0005654 ISO
    MCM complex GO:0042555 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Mcm4 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Mcm4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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