Gene description for Mog
Gene name myelin oligodendrocyte glycoprotein
Gene symbol Mog
Other names/aliases B230317G11Rik
Species Mus musculus
 Database cross references - Mog
ExoCarta ExoCarta_17441
Vesiclepedia VP_17441
Entrez Gene 17441
UniProt Q61885  
 Mog identified in exosomes derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Mog
Molecular Function
    signaling receptor binding GO:0005102 IBA
Biological Process
    regulation of cytokine production GO:0001817 IBA
    cell adhesion GO:0007155 IEA
    T cell receptor signaling pathway GO:0050852 IBA
Subcellular Localization
    external side of plasma membrane GO:0009897 IBA
    cell surface GO:0009986 ISO
    membrane GO:0016020 IEA
    myelin sheath GO:0043209 HDA
 Experiment description of studies that identified Mog in exosomes
1
Experiment ID 33
MISEV standards
EM|IEM
Biophysical techniques
Alix|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Mog
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 Shank3  
Affinity Capture-MS Mus musculus
3 Mapt  
Affinity Capture-MS Mus musculus
4 Prnp 19122
Affinity Capture-MS Mus musculus
5 Tia1  
Affinity Capture-MS Mus musculus
6 Hdac4  
Affinity Capture-MS Mus musculus
7 Htt  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Mog is involved
No pathways found





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