Gene description for COX2
Gene name cytochrome c oxidase II, mitochondrial
Gene symbol COX2
Other names/aliases -
Species Mus musculus
 Database cross references - COX2
ExoCarta ExoCarta_17709
Entrez Gene 17709
UniProt P00405  
 COX2 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for COX2
Molecular Function
    metal ion binding GO:0046872 IEA
    copper ion binding GO:0005507 IEA
    oxidoreductase activity GO:0016491 IEA
    cytochrome-c oxidase activity GO:0004129 IEA
Biological Process
    electron transport chain GO:0022900 IEA
    oxidation-reduction process GO:0055114 IEA
    transport GO:0006810 IEA
Subcellular Localization
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 IEA
    integral component of membrane GO:0016021 IEA
    respiratory chain GO:0070469 IEA
    membrane GO:0016020 IEA
 Experiment description of studies that identified COX2 in exosomes
1
Experiment ID 188
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH|UCHL1|HSP90
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COX2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COX2 is involved
PathwayEvidenceSource
Respiratory electron transport IEA Reactome
TP53 Regulates Metabolic Genes IEA Reactome





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