Gene description for Nes
Gene name nestin
Gene symbol Nes
Other names/aliases AA166324
Species Mus musculus
 Database cross references - Nes
ExoCarta ExoCarta_18008
Entrez Gene 18008
UniProt Q6P5H2  
 Nes identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Nes
Molecular Function
    CCR5 chemokine receptor binding GO:0031730 ISO
    protein binding GO:0005515 IPI
    structural molecule activity GO:0005198 IEA
Biological Process
    nervous system development GO:0007399 IDA
    multicellular organismal development GO:0007275 IEA
    cell projection morphogenesis GO:0048858 IMP
    negative regulation of neuron apoptotic process GO:0043524 IMP
Subcellular Localization
    intermediate filament GO:0005882 ISO
    intracellular GO:0005622 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified Nes in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Nes
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nes is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here