Gene description for Nfatc2ip
Gene name nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
Gene symbol Nfatc2ip
Other names/aliases D7Ertd304e
NIP45
Species Mus musculus
 Database cross references - Nfatc2ip
ExoCarta ExoCarta_18020
Entrez Gene 18020
UniProt O09130  
 Nfatc2ip identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nfatc2ip
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    cytokine production GO:0001816 IDA
Subcellular Localization
    nucleus GO:0005634 IC
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Nfatc2ip in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nfatc2ip
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nfatc2ip is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here