Gene description for Luc7l2
Gene name LUC7-like 2 (S. cerevisiae)
Gene symbol Luc7l2
Other names/aliases 4930471C18Rik
AA522013
AU015269
CGI59
Cgi74
Species Mus musculus
 Database cross references - Luc7l2
ExoCarta ExoCarta_192196
Vesiclepedia VP_192196
Entrez Gene 192196
UniProt Q7TNC4  
 Luc7l2 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Luc7l2
Molecular Function
    mRNA binding GO:0003729 IBA
    mRNA binding GO:0003729 IEA
    enzyme binding GO:0019899 IEA
    enzyme binding GO:0019899 ISO
Biological Process
    mRNA splice site recognition GO:0006376 IBA
    mRNA splice site recognition GO:0006376 IEA
Subcellular Localization
    U1 snRNP GO:0005685 IBA
    U1 snRNP GO:0005685 IEA
    nuclear speck GO:0016607 IDA
    U2-type prespliceosome GO:0071004 IBA
 Experiment description of studies that identified Luc7l2 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Luc7l2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Fancd2  
Affinity Capture-MS Mus musculus
2 Atxn1  
Affinity Capture-MS Mus musculus
3 Htt  
Affinity Capture-MS Mus musculus
4 Cars 27267
Co-fractionation Mus musculus
5 Hspa4l  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Luc7l2 is involved
No pathways found





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