Gene description for Cars
Gene name
cysteinyl-tRNA synthetase
Gene symbol
Cars
Other names/aliases
CA3
Species
Mus musculus
Database cross references - Cars
ExoCarta
ExoCarta_27267
Vesiclepedia
VP_27267
Entrez Gene
27267
UniProt
Q9ER72
Cars identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Cars
Experiment description of studies that identified Cars in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Cars
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Thumpd3
Co-fractionation
Mus musculus
2
Luc7l2
192196
Co-fractionation
Mus musculus
3
Atg16l1
Affinity Capture-MS
Mus musculus
4
Xpo7
Co-fractionation
Mus musculus
5
Ppm1g
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Cars is involved
No pathways found