Gene description for Ptgs1
Gene name	prostaglandin-endoperoxide synthase 1
Gene symbol	Ptgs1
Other names/aliases	COX1 Cox-1 Cox-3 PGHS-1 PHS 1 Pghs1
Species	Mus musculus
Database cross references - Ptgs1
ExoCarta	ExoCarta_19224
Entrez Gene	19224
UniProt	P22437
Ptgs1 identified in exosomes derived from the following tissue/cell type
Basophilic leukemia cells	20424270

Gene ontology annotations for Ptgs1

Molecular Function     oxidoreductase activity GO:0016491 IEA     prostaglandin-endoperoxide synthase activity GO:0004666 ISO     metal ion binding GO:0046872 IEA     peroxidase activity GO:0004601 IEA     dioxygenase activity GO:0051213 IEA     lipid binding GO:0008289 ISO     heme binding GO:0020037 IEA Biological Process     oxidation-reduction process GO:0055114 ISO     learning GO:0007612 ISO     negative regulation of epinephrine secretion GO:0032811 ISO     regulation of cell proliferation GO:0042127 IGI     cyclooxygenase pathway GO:0019371 ISO     positive regulation of vasoconstriction GO:0045907 ISO     prostaglandin biosynthetic process GO:0001516 ISO     response to oxidative stress GO:0006979 IEA     negative regulation of norepinephrine secretion GO:0010700 ISO     positive regulation of smooth muscle contraction GO:0045987 ISO     maintenance of blood-brain barrier GO:0035633 ISO     memory GO:0007613 ISO     regulation of blood pressure GO:0008217 IMP     prostaglandin metabolic process GO:0006693 IMP     lipid metabolic process GO:0006629 IEA     fatty acid biosynthetic process GO:0006633 IEA     keratinocyte differentiation GO:0030216 NAS     inflammatory response GO:0006954 IEA     sensory perception of pain GO:0019233 ISO     fatty acid metabolic process GO:0006631 IEA Subcellular Localization     nucleus GO:0005634 IDA     photoreceptor outer segment GO:0001750 IDA     extracellular exosome GO:0070062 ISO     cytoplasm GO:0005737 ISO     endoplasmic reticulum GO:0005783 IEA     nuclear envelope GO:0005635 ISO     intracellular membrane-bounded organelle GO:0043231 IEA     membrane GO:0016020 IEA