Gene description for Nucb1
Gene name nucleobindin 1
Gene symbol Nucb1
Other names/aliases B230337F23Rik
Species Mus musculus
 Database cross references - Nucb1
ExoCarta ExoCarta_18220
Entrez Gene 18220
UniProt Q02819  
 Nucb1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Nucb1
Molecular Function
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
    G-protein alpha-subunit binding GO:0001965 ISO
    calcium ion binding GO:0005509 ISO
Biological Process
    regulation of protein targeting GO:1903533 ISO
Subcellular Localization
    early endosome GO:0005769 ISO
    extracellular space GO:0005615 ISO
    trans-Golgi network GO:0005802 ISO
    Golgi apparatus GO:0005794 ISO
    cis-Golgi network GO:0005801 ISO
    extracellular exosome GO:0070062 ISO
    nucleus GO:0005634 ISO
    extracellular region GO:0005576 ISO
    membrane GO:0016020 ISO
    microtubule cytoskeleton GO:0015630 ISO
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    rough endoplasmic reticulum GO:0005791 ISO
    Golgi-associated vesicle GO:0005798 ISO
    Golgi cisterna membrane GO:0032580 ISO
    cytoplasm GO:0005737 ISO
    extrinsic component of Golgi membrane GO:0090498 ISO
    lumenal side of Golgi membrane GO:0098547 ISO
 Experiment description of studies that identified Nucb1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Nucb1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Nucb1 is involved
No pathways found

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