Gene description for MPZL3
Gene name myelin protein zero-like 3
Gene symbol MPZL3
Other names/aliases -
Species Homo sapiens
 Database cross references - MPZL3
ExoCarta ExoCarta_196264
Entrez Gene 196264
HGNC 27279
MIM 611707
UniProt Q6UWV2  
 MPZL3 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for MPZL3
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    hair cycle GO:0042633 IEA
    extracellular matrix organization GO:0030198 IEA
    cell adhesion GO:0007155 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified MPZL3 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for MPZL3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MPZL3 is involved
No pathways found





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