Gene description for Rbmxl1
Gene name RNA binding motif protein, X linked-like-1
Gene symbol Rbmxl1
Other names/aliases Hnrpg
Rbmx
Rbmxrt
Species Mus musculus
 Database cross references - Rbmxl1
ExoCarta ExoCarta_19656
Entrez Gene 19656
UniProt Q91VM5  
 Rbmxl1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rbmxl1
Molecular Function
    chromatin binding GO:0003682 IDA
    core promoter binding GO:0001047 IDA
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
    nucleic acid binding GO:0003676 IEA
    RNA binding GO:0003723 ISO
Biological Process
    RNA splicing GO:0008380 IEA
    mRNA splice site selection GO:0006376 ISO
    protein homooligomerization GO:0051260 ISO
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IMP
    mRNA processing GO:0006397 IEA
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 ISO
    negative regulation of mRNA splicing, via spliceosome GO:0048025 ISO
    positive regulation of mRNA splicing, via spliceosome GO:0048026 ISO
Subcellular Localization
    nucleus GO:0005634 IDA
    ribonucleoprotein complex GO:0030529 IEA
    supraspliceosomal complex GO:0044530 ISO
 Experiment description of studies that identified Rbmxl1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rbmxl1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Rbmxl1 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway IEA Reactome
Processing of Capped Intron-Containing Pre-mRNA IEA Reactome





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