Gene description for Sntb2
Gene name syntrophin, basic 2
Gene symbol Sntb2
Other names/aliases Snt2
Species Mus musculus
 Database cross references - Sntb2
ExoCarta ExoCarta_20650
Vesiclepedia VP_20650
Entrez Gene 20650
UniProt Q61235  
 Sntb2 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Sntb2
Molecular Function
    actin binding GO:0003779 IEA
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 IEA
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 ISO
    Golgi apparatus GO:0005794 ISO
    microtubule GO:0005874 IEA
    plasma membrane GO:0005886 ISO
    dystrophin-associated glycoprotein complex GO:0016010 IBA
    transport vesicle membrane GO:0030658 IEA
    protein-containing complex GO:0032991 ISO
    synapse GO:0045202 IBA
    synapse GO:0045202 IDA
    anchoring junction GO:0070161 IEA
 Experiment description of studies that identified Sntb2 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Sntb2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Utrn  
Reconstituted Complex Mus musculus
2 Dtna  
Reconstituted Complex Mus musculus
3 Nos1  
Far Western Mus musculus
4 Dtnb 13528
Reconstituted Complex Mus musculus
5 Dmd  
Affinity Capture-MS Mus musculus
Affinity Capture-Western Mus musculus
Reconstituted Complex Mus musculus
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Sntb2 is involved
No pathways found





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