Gene description for Bptf
Gene name bromodomain PHD finger transcription factor
Gene symbol Bptf
Other names/aliases 9430093H17Rik
Falz
Species Mus musculus
 Database cross references - Bptf
ExoCarta ExoCarta_207165
Vesiclepedia VP_207165
Entrez Gene 207165
 Bptf identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Bptf
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    ATP-dependent activity, acting on DNA GO:0008094 ISO
    transcription factor binding GO:0008134 ISO
    methylated histone binding GO:0035064 IBA
    sequence-specific DNA binding GO:0043565 ISO
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 ISO
    embryonic placenta development GO:0001892 IMP
    chromatin remodeling GO:0006338 ISO
    regulation of DNA-templated transcription GO:0006355 ISO
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    regulation of transcription by RNA polymerase II GO:0006357 ISO
    brain development GO:0007420 ISO
    endoderm development GO:0007492 IMP
    anterior/posterior pattern specification GO:0009952 IMP
    positive regulation of transcription by RNA polymerase II GO:0045944 ISO
Subcellular Localization
    chromatin GO:0000785 ISO
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
    NURF complex GO:0016589 IBA
    NURF complex GO:0016589 ISO
    dendrite GO:0030425 ISO
    cell body GO:0044297 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    ATPase complex GO:1904949 ISO
 Experiment description of studies that identified Bptf in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Bptf
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Elf5  
Affinity Capture-MS Mus musculus
2 Foxp3  
Affinity Capture-MS Mus musculus
3 H3f3a 15078
Affinity Capture-Western Mus musculus
4 Pou5f1  
Affinity Capture-MS Mus musculus
5 Srf  
Affinity Capture-Western Mus musculus
6 Nanog  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
7 Tfcp2l1  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Bptf is involved
No pathways found





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