Gene description for Bptf
Gene name bromodomain PHD finger transcription factor
Gene symbol Bptf
Other names/aliases 9430093H17Rik
Falz
Species Mus musculus
 Database cross references - Bptf
ExoCarta ExoCarta_207165
Entrez Gene 207165
 Bptf identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Bptf
Molecular Function
    sequence-specific DNA binding GO:0043565 ISO
    transcription factor binding GO:0008134 ISO
    DNA-dependent ATPase activity GO:0008094 ISO
Biological Process
    brain development GO:0007420 ISO
    regulation of transcription, DNA-templated GO:0006355 ISO
    transcription, DNA-templated GO:0006351 ISO
    positive regulation of transcription, DNA-templated GO:0045893 ISO
    anterior/posterior pattern specification GO:0009952 IMP
    chromatin remodeling GO:0006338 ISO
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISO
    endoderm development GO:0007492 IMP
    embryonic placenta development GO:0001892 IMP
Subcellular Localization
    NURF complex GO:0016589 ISO
    nucleoplasm GO:0005654 ISO
    perinuclear region of cytoplasm GO:0048471 ISO
    cytoplasm GO:0005737 ISO
    nucleus GO:0005634 ISO
    cell body GO:0044297 ISO
    extracellular exosome GO:0070062 ISO
    neuron projection GO:0043005 ISO
    dendrite GO:0030425 ISO
 Experiment description of studies that identified Bptf in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Bptf
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Bptf is involved
No pathways found





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