Gene description for Tacc3
Gene name transforming, acidic coiled-coil containing protein 3
Gene symbol Tacc3
Other names/aliases Aint
C86661
Eric1
Species Mus musculus
 Database cross references - Tacc3
ExoCarta ExoCarta_21335
Vesiclepedia VP_21335
Entrez Gene 21335
 Tacc3 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Tacc3
Molecular Function
    protein domain specific binding GO:0019904 IPI
    protein binding GO:0005515 IPI
Biological Process
    astral microtubule organization GO:0030953 IDA
    cerebral cortex development GO:0021987 IMP
    response to hypoxia GO:0001666 IDA
    regulation of cell cycle GO:0051726 IGI
    microtubule cytoskeleton organization GO:0000226 IMP
    neurogenesis GO:0022008 IMP
    regulation of microtubule-based process GO:0032886 IMP
    interkinetic nuclear migration GO:0022027 IMP
    cell proliferation GO:0008283 IMP
    hemopoiesis GO:0030097 IMP
    cytoplasmic sequestering of transcription factor GO:0042994 IDA
Subcellular Localization
    microtubule cytoskeleton GO:0015630 IBA
    centrosome GO:0005813 TAS
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Tacc3 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Tacc3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tacc3 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here