Gene description for Tcea1
Gene name transcription elongation factor A (SII) 1
Gene symbol Tcea1
Other names/aliases S-II
Species Mus musculus
 Database cross references - Tcea1
ExoCarta ExoCarta_21399
Entrez Gene 21399
UniProt P10711  
 Tcea1 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Tcea1
Molecular Function
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    metal ion binding GO:0046872 IEA
    nucleic acid binding GO:0003676 IEA
Biological Process
    regulation of transcription from RNA polymerase II promoter GO:0006357 IEA
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 IEA
    erythrocyte differentiation GO:0030218 IMP
    regulation of DNA-templated transcription, elongation GO:0032784 IEA
    positive regulation of transcription, DNA-templated GO:0045893 IDA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
Subcellular Localization
    nucleolus GO:0005730 ISO
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified Tcea1 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tcea1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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