Gene description for Ugp2
Gene name UDP-glucose pyrophosphorylase 2
Gene symbol Ugp2
Other names/aliases UDPGP
Species Mus musculus
 Database cross references - Ugp2
ExoCarta ExoCarta_216558
Entrez Gene 216558
UniProt Q91ZJ5  
 Ugp2 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Ugp2
Molecular Function
    UTP:glucose-1-phosphate uridylyltransferase activity GO:0003983 ISO
    glucose binding GO:0005536 ISO
    transferase activity GO:0016740 IEA
    pyrimidine ribonucleotide binding GO:0032557 ISO
    uridylyltransferase activity GO:0070569 IEA
    metal ion binding GO:0046872 IEA
    nucleotidyltransferase activity GO:0016779 IEA
    identical protein binding GO:0042802 ISO
Biological Process
    metabolic process GO:0008152 IEA
    UDP-glucose metabolic process GO:0006011 ISO
    glucose 1-phosphate metabolic process GO:0019255 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Ugp2 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ugp2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ugp2 is involved
Formation of the active cofactor, UDP-glucuronate IEA Reactome
Glycogen synthesis IEA Reactome

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